请使用支持JavaScript的浏览器! mdbioproducts-antibodies-MD Bioproducts/Citrullinated Collagen Type II Antibody (Clone ACC-1)/1041003/100 ug
主营:细胞培养相关试剂 (胶原蛋白、细胞增殖检测、支原体PCR检测)、疾病诱导试剂
banner
当前位置: 首页 > 产品中心 > antibodies > MD Bioproducts/Citrullinated Collagen Type II Antibody (Clone ACC-1)/1041003/100 ug
公司介绍
MD Biosciences成立于1991年,总部位于瑞士,在美国、加拿大和英国设有办事处。旗下MD Bioproducts部门主要产品涉及肿瘤、心血管、细胞培养、内分泌、炎症、代谢疾病、神经科学、疼痛、肾脏/肝脏功能等领域。产品包括抗体(软骨蛋白聚糖、胶原蛋白、激素、神经药物)、细胞培养相关试剂(胶原蛋白、细胞增殖检测、支原体PCR检测)、疾病诱导试剂(关节炎诱导抗体混合、弗氏佐剂、胶原蛋白II等)、ELISA试剂盒、同型对照、天然蛋白以及重组蛋白。
问答列表

    暂无问答

MD Bioproducts/Citrullinated Collagen Type II Antibody (Clone ACC-1)/1041003/100 ug

  • 产品编号: 1041003
  • 美  元  价: $0.00
  • 会  员  价: 待定
  • 品       牌: MD Bioproducts
  • 产       地: 美国
  • 公       司: MD Bioproducts
  • 产品分类: ref="." class="index">首页 > MD Bioproducts/Citrullinated Collagen Type II Antibody (Clone ACC-1)/1041003/100 ug
  • 公司分类: antibodies
:100 ug
MD Bioproducts/Citrullinated Collagen Type II Antibody (Clone ACC-1)/1041003/100 ug
  • MD Bioproducts/Citrullinated Collagen Type II Antibody (Clone ACC-1)/1041003/100 ug
商品介绍
Overview: 

The citrullination of proteins is a post-translational modification where peptidyl arginine residues are converted to peptidyl citrulline by a family of enzymes called peptidyl arginine deiminases (PADs). Citrullination can be found in multiple tissue types and has been shown to occur in both human and mouse inflamed joints (1,2, 3). Proteins are susceptIBLe to citrullination during inflammatory processes and an autoantibody response to citrullinated proteins is a hallmark of Rheumatoid Arthritis (RA). Antibodies against citrullinated proteins (ACPAs) can be found in 50-70% of all RA patients and have a high diagnostic value as a bioMarker for detecting RA early (4,5). Current research is focused on understanding the detailed mechanisms causing direct inflammation of the joints and the self-perpetuating behavior of RA, via the recognition of post-translation modifications such as citrullination by T and B cells.

Data/Specifications: 

Immunogen: Citrullinated collagen type II peptide

 

Clone: ACC-1

 

Host: Mouse

 

Isotype: IgG2a

 

Specificity: The antibody binds to the triple helical citrullinated C1 epitope of CII. The C1 epitope containes 2 arginines which can be postranslationally converted to citrulline. This antibody will recognize the 2nd citrulline at position 365. Cross-reactivity is exhibited with denatured CII as well as denatured C1 epitope.

 

Purity: Protein A purified

 

Form: Liquid, 1 mL/vial

 

Concentration: 0.1 mg/mL

 

Storage: -20° C

How_To_Use:

 

Applications

 

 

品牌介绍

MD Biosciences成立于1991年,总部位于瑞士,在美国、加拿大和英国设有办事处。旗下MD Bioproducts部门主要产品涉及肿瘤、心血管、细胞培养、内分泌、炎症、代谢疾病、神经科学、疼痛、肾脏/肝脏功能等领域。产品包括抗体 (软骨蛋白聚糖、胶原蛋白、激素、神经药物)、细胞培养相关试剂 (胶原蛋白、细胞增殖检测、支原体PCR检测)、疾病诱导试剂 (关节炎诱导抗体混合、弗氏佐剂、胶原蛋白II等)、ELISA试剂盒、同型对照、天然蛋白以及重组蛋白。

自营商城图标
厂家直采
全球直采模式 正品优价
正品保障图标
正品保障
厂家直发 有线跟踪
解放采购图标
正规清关
CIF100%正规报关,提供发票
及时交付图标
及时交付
限时必达 不达必赔
在线客服
客服电话

4000-520-616

微信交流