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MD Biosciences成立于1991年,总部位于瑞士,在美国、加拿大和英国设有办事处。旗下MD Bioproducts部门主要产品涉及肿瘤、心血管、细胞培养、内分泌、炎症、代谢疾病、神经科学、疼痛、肾脏/肝脏功能等领域。产品包括抗体 (软骨蛋白聚糖、胶原蛋白、激素、神经药物)、细胞培养相关试剂 (胶原蛋白、细胞增殖检测、支原体PCR检测)、疾病诱导试剂 (关节炎诱导抗体混合、弗氏佐剂
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MD Bioproducts/Collagen Type I and III, Rat/8052003/10 mg

MD Bioproducts/Collagen Type I and III, Rat/8052003/10 mg
  • MD Bioproducts/Collagen Type I and III, Rat/8052003/10 mg
商品介绍
Overview: 

TypeIcollagenisthemostabundantcollagenandisfoundinconnectivetissuesincludingtendon,ligament,dermisandbloodvessel.Itisthemajorcomponentandtheprimarydeterminantoftensilestrengthoftheextracelluarmatrix(ECM).Itiswidelyusedasathinlayerontissue-culturesurfacestoenhancetheattachmentandproliferationofavarietyofcellsincludingendothelialcells,fibroblasts,hepatocytes,epithelialcellsetc.Inaddition,collagenIcanself-assembleintoa3-Dsuperamoleculargelinvitro,makingitanidealBIOLOGicalscaffoldtopromotemoreinvivo-likecellularmorphologyandfunction.

TypeIIIcollagenisthesecondmostabundantcollagenintissuesandisfoundmostcommonlyintissuesexhibitingelasticpropertiessuchasskin,lungs,intestinalwallsandwallsofbloodvessels.Itisahomotrimercomprisedofthreealpha-1chainsandresemblesotherfibrillarcollagensinstructureandfunction.Itissynthesizedasprocollagen,similarytocollagenI,buttheN-terminalpropeptideremainsattachedinthematurefibrillartypeIIIform.

 

Symbols/RelatedTerms:

 

  • COL1A1
  • COL1A2
  • COL3A1
  • CollagentypeIII,alpha1
  • osteogenesisimperfecta

 

 

Data/Specifications: 

 

Purity: 

RatcollagentypeI-90%

RatcollagentypeIII-10%

Othercollagens-below1%

Non-collagenproteins-below0.5%

 

Form:10mglyophilized,salt-free

 

Purification: Partialpepsindigestioninacidicconditionsanddifferentialsaltprecipitation.

 

Reconstitution: Use0.5Maceticacid,pH2.5.Dissolvedcollagenretainsimmunologicpropertiesofnativecollagen.StructureofnativecollagenconfirmedbyABIlitytoformmicrofibrils.

 

Storage: Collagendissolvedinaceticacidisstableat4°Cfor1month.Lyophilizedcollagenlongtermstorage(2years)at-20°Corlower.

How_To_Use:

KeyApplicatons:

  • Coatingmaterialforcellculturestudies. 

Note:Maynotbesuitablefor3-Dgelformation.

品牌介绍

MD Biosciences成立于1991年,总部位于瑞士,在美国、加拿大和英国设有办事处。旗下MD Bioproducts部门主要产品涉及肿瘤、心血管、细胞培养、内分泌、炎症、代谢疾病、神经科学、疼痛、肾脏/肝脏功能等领域。产品包括抗体 (软骨蛋白聚糖、胶原蛋白、激素、神经药物)、细胞培养相关试剂 (胶原蛋白、细胞增殖检测、支原体PCR检测)、疾病诱导试剂 (关节炎诱导抗体混合、弗氏佐剂、胶原蛋白II等)、ELISA试剂盒、同型对照、天然蛋白以及重组蛋白。

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