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主营:细胞培养相关试剂 (胶原蛋白、细胞增殖检测、支原体PCR检测)、疾病诱导试剂
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MD Biosciences成立于1991年,总部位于瑞士,在美国、加拿大和英国设有办事处。旗下MD Bioproducts部门主要产品涉及肿瘤、心血管、细胞培养、内分泌、炎症、代谢疾病、神经科学、疼痛、肾脏/肝脏功能等领域。产品包括抗体(软骨蛋白聚糖、胶原蛋白、激素、神经药物)、细胞培养相关试剂(胶原蛋白、细胞增殖检测、支原体PCR检测)、疾病诱导试剂(关节炎诱导抗体混合、弗氏佐剂、胶原蛋白II等)、ELISA试剂盒、同型对照、天然蛋白以及重组蛋白。
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MD Bioproducts/Collagen Type II, Bovine, Lyophilized/804001-lyo/10 mg

  • 产品编号: 804001-lyo
  • 美  元  价: $0.00
  • 会  员  价: 待定
  • 品       牌: MD Bioproducts
  • 产       地: 美国
  • 公       司: MD Bioproducts
  • 产品分类: ref="." class="index">首页 > MD Bioproducts/Collagen Type II, Bovine, Lyophilized/804001-lyo/10 mg
  • 公司分类: natural and recombinant proteins
:10 mg
MD Bioproducts/Collagen Type II, Bovine, Lyophilized/804001-lyo/10 mg
  • MD Bioproducts/Collagen Type II, Bovine, Lyophilized/804001-lyo/10 mg
商品介绍
Overview: 

Type II collagen (CII) is a fibrillar collagen that is primarily located in cartilage tissue. The major molecular form of collagen in cartilage is type II collagen. Type II collagen is also located in the vitreous humor of the eye, the inner ear, the nose, and the intervertebral discs of the spine. The function of type II collagen is to provide tensile strength and give cartilage the ABIlity to resist shearing forces. Mutations of the COL2A1 gene affect the synthesis of type II collagen and cause chondrodysplasias. This is characterized by abnormal cartilage that leads to bone and joint deformities. The degradation of collagen type II is an early indicator of osteoarthritis.

 

Type II Collagen and Adjuvent Susceptibility to CIA is linked to MHC class II molecules and is dependent upon the species of type II collagen used for immunization. Various species of highly purified Type II Collagen are supplied lyophilized and in solution for use in the induction of arthritis in vivo.

 

Symbols/Related Terms:

 

  • COL2A1
  • pro-alpha 1(II) chain
  • Achondrogenesis
  • Hypochondrogenesis
  • Spondyloepimetaphyseal dysplasia
  • Osteoarthritis (OA)
  • Collagen Induced Arthritis (CIA)

 

 

Data/Specifications: 

Concentration: Can be reconstituted to concentration of choice.

Purity: >99% as determined by SDS-PAGE and visualized by Coomassie blue staining

Purification: Differential salt precipitation

Source: Fetal bovine articular cartilage

Form: lyophilized

How_To_Use:

Key Applicatons:

 

  • Induction of arthritis in vivo
  • Attachment and differentiation of chondrocytes
  • Cell culture
  • ELISA standard/plate coating

 

品牌介绍

MD Biosciences成立于1991年,总部位于瑞士,在美国、加拿大和英国设有办事处。旗下MD Bioproducts部门主要产品涉及肿瘤、心血管、细胞培养、内分泌、炎症、代谢疾病、神经科学、疼痛、肾脏/肝脏功能等领域。产品包括抗体 (软骨蛋白聚糖、胶原蛋白、激素、神经药物)、细胞培养相关试剂 (胶原蛋白、细胞增殖检测、支原体PCR检测)、疾病诱导试剂 (关节炎诱导抗体混合、弗氏佐剂、胶原蛋白II等)、ELISA试剂盒、同型对照、天然蛋白以及重组蛋白。

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